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Novel lysosome-targeted anticancer fluorescent agents used in zebrafish and nude mouse tumour imaging

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 112-120 doi: 10.1007/s11705-021-2075-5

Abstract: both reporting and imaging agents in vitro and in vivo without the need to add other fluorescent

Keywords： fluorescent drug     lysosomal     anticancer     zebrafish     nude-mouse tumour imaging    

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Information gathering and processing with fluorescent molecules

Brian DALY,Jue LING,A. Prasanna de SILVA

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 2,   Pages 240-251 doi: 10.1007/s11705-014-1432-z

Abstract: Molecular information gathering and processing — a young field of applied chemistry — is undergoing good growth. The progress is occurring both in terms of conceptual development and in terms of the strengthening of older concepts with new examples. This review critically surveys these two broad avenues. We consider some cases where molecules emulate one of the building blocks of electronic logic gates. We then examine molecular emulation of various Boolean logic gates carrying one, two or three inputs. Some single-input gates are popular information gathering devices. Special systems, such as ‘lab-on-a-molecule’ and molecular keypad locks, also receive attention. A situation deviating from the Boolean blueprint is also discussed. Some pointers are offered for maintaining the upward curve of the field.

Keywords： molecular logic     molecular computation     molecular sensor     fluorescent molecular device     fluorescent sensor    

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Recent advances of small-molecule fluorescent probes for detecting biological hydrogen sulfide

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 34-63 doi: 10.1007/s11705-021-2050-1

Abstract: has realized the study of H2S in subcellular organelles, facilitated by the development of fluorescent

Keywords： hydrogen sulfide     fluorescent probe     reducibility     nucleophilicity     copper sulfide precipitate     hydrogen    

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Fluorescent properties and

Hong GAO,Jie SONG,Shibin SHANG,Zhanqian SONG

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 1,   Pages 106-115 doi: 10.15302/J-FASE-2017133

Abstract: series of dehydroabietic acid-based diarylamines have been synthesized in order to investigate their fluorescentmolecular geometry, HOMO and LUMO energies, and energy gaps are important to predict absorption and fluorescentcarcinoma SMMC-7721, human gastric cancer SGC-7901 and human lung adenocarcinoma A549 cells and strong blue fluorescentThese compounds are potential candidates for fluorescent probes in biological diagnosis.

Keywords： dehydroabietic acid-based diarylamine     DFT study     fluorescent probe     in vitro imaging    

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A novel flavonol-based colorimetric and turn-on fluorescent probe for rapid determination of hydrazine

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 1,   Pages 24-33 doi: 10.1007/s11705-022-2171-1

Abstract: Herein, a novel fluorescent probe 4-oxo-2-styryl-4H-chromen-3-yl thiophene-2-carboxylate (FHTstrips were able to conveniently detect hydrazine of low concentration through distinct naked-eye and fluorescent

Keywords： cinnamaldehyde     3-hydroxychromone derivative     hydrazine     fluorescent probe    

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Fluorescent probes and functional materials for biomedical applications

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 10,   Pages 1425-1437 doi: 10.1007/s11705-022-2163-1

Abstract: Due to their simplicity in preparation, sensitivity and selectivity, fluorescent probes have become theIn addition, many long-wavelength fluorescent probes developed have also proven applicable for inHere, we highlight examples of fluorescent probes and functional materials for biological applicationsselected from the special issues “Fluorescent Probes” and “Molecular Sensors and Logic Gates” recently

Keywords： fluorescent probes     imaging     cell     biomedicine     biomolecules    

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Taking advantage of drug resistance, a new approach in the war on cancer

Liqin Wang, Rene Bernards

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 490-495 doi: 10.1007/s11684-018-0647-7

Abstract: case with conventional chemotherapies, the effectiveness of these drugs is limited by the emergence of drug-resistantWhile most cancer therapies are given in combinations that are designed to avoid drug resistance, wetherapeutic approaches that take advantage of the changes in cancer cells that arise upon development of drugThis approach is based on notion that drug resistance comes at a fitness cost to the cancer cell thatWe discuss the development of sequential drug therapies in which the first therapy is not given with

Keywords： cancer     drug resistance     genetic screens     senescence     targeted therapy    

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Biodegradable polymethacrylic acid grafted psyllium for controlled drug delivery systems

Ranvijay KUMAR, Kaushlendra SHARMA

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 1,   Pages 116-122 doi: 10.1007/s11705-013-1310-0

Abstract: acid was incorporated in the various Psy- -PMA samples and tablets were prepared to study the in vitro drugIn addition, the biodegradable Psy- -PMA had the highest drug release in the acidic medium.This may be attributed to Fickian diffusion since the drug and the medium in which it was released have

Keywords： psyllium     acetyl salicylic acid     in-vitro drug release     swelling     biodegradation    

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A highly selective fluorescent probe for real-time imaging of UDP-glucuronosyltransferase 1A8 in living

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 103-111 doi: 10.1007/s11705-021-2064-8

Abstract: Here, a novel fluorescent probe BDMP was developed based on boron-dipyrromethene (BODIPY) with high sensitivity

Keywords： UDP-glucuronosyltransferase 1A8     fluorescent probe     subtype selectivity     fluorescence imaging    

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Special issue on “Fluorescent probes”

Adam C. Sedgwick, Tony D. James

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 1,   Pages 1-3 doi: 10.1007/s11705-019-1910-4

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Protein microspheres for pulmonary drug delivery

Yongda SUN,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 1,   Pages 82-86 doi: 10.1007/s11705-009-0307-1

Abstract: supercritical fluid (SCF) technique was developed for the preparation of microspheres for pulmonary drugleading to a dry fine powder with good particle size distribution and near ideal morphology for pulmonary drug

Keywords： advanced engineering     improved     pressure     aqueous     technique    

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Semi-solid materials for controlled release drug formulation: current status and future prospects

Michelle TRAN,Chun WANG

Frontiers of Chemical Science and Engineering 2014, Volume 8, Issue 2,   Pages 225-232 doi: 10.1007/s11705-014-1429-7

Abstract: These polymers are selected based on their importance and broad scope of application in FDA-approved drugGlyceride-based polymers used in self-emulsifying drug delivery systems (SEDDS) will also be discussed

Keywords： controlled release     drug delivery     semi-solids     polymer     excipient    

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Nanostructured hollow spheres of hydroxyapatite: preparation and potential application in drug delivery

Xiaojing ZHANG, Weixin ZHANG, Zeheng YANG, Zhao ZHANG

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 3,   Pages 246-252 doi: 10.1007/s11705-012-1299-9

Abstract: The properties of the different kinds of spheres as drug delivery carriers were evaluated.Ibuprofen (IBU) was chosen as the model drug to load into the HA samples.The HA hollow spheres exhibited a higher drug loading capacity and more favorable release propertiesthan the HA solid spheres and thus are very promising for controlled drug release applications.

Keywords： hydroxyapatite     hollow spheres     synthesis     drug release    

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Recent advances in small molecule fluorescent probes for simultaneous imaging of two bioactive molecules

Yongqing Zhou, Xin Wang, Wei Zhang, Bo Tang, Ping Li

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 1,   Pages 4-33 doi: 10.1007/s11705-021-2041-2

Abstract: Single organic molecule fluorescent probes have been successively developed to simultaneously monitoron summarizing the design strategies, classifications, and bioimaging applications of dual-response fluorescent

Keywords： bioactive molecules     fluorescent probes     in living cells and in vivo     review    

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Prevalence of antifolate drug resistance markers in in China

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 83-92 doi: 10.1007/s11684-021-0894-x

Abstract: dhps) genes of Plasmodium vivax and antifolate resistance-associated genes were used for drugvivax parasites were different across China and molecular markers could be used to rapidly monitor drugResults provided evidence for updating national drug policy and treatment guidelines.

Keywords： drug resistance     antifolates     molecular markers     Plasmodium vivax     China    

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Title Author Date Type Operation

Novel lysosome-targeted anticancer fluorescent agents used in zebrafish and nude mouse tumour imaging

Journal Article

Information gathering and processing with fluorescent molecules

Brian DALY,Jue LING,A. Prasanna de SILVA

Journal Article

Recent advances of small-molecule fluorescent probes for detecting biological hydrogen sulfide

Journal Article

Fluorescent properties and

Hong GAO,Jie SONG,Shibin SHANG,Zhanqian SONG

Journal Article

A novel flavonol-based colorimetric and turn-on fluorescent probe for rapid determination of hydrazine

Journal Article

Fluorescent probes and functional materials for biomedical applications

Journal Article

Taking advantage of drug resistance, a new approach in the war on cancer

Liqin Wang, Rene Bernards

Journal Article

Biodegradable polymethacrylic acid grafted psyllium for controlled drug delivery systems

Ranvijay KUMAR, Kaushlendra SHARMA

Journal Article

A highly selective fluorescent probe for real-time imaging of UDP-glucuronosyltransferase 1A8 in living

Journal Article

Special issue on “Fluorescent probes”

Adam C. Sedgwick, Tony D. James

Journal Article

Protein microspheres for pulmonary drug delivery

Yongda SUN,

Journal Article

Semi-solid materials for controlled release drug formulation: current status and future prospects

Michelle TRAN,Chun WANG

Journal Article

Nanostructured hollow spheres of hydroxyapatite: preparation and potential application in drug delivery

Xiaojing ZHANG, Weixin ZHANG, Zeheng YANG, Zhao ZHANG

Journal Article

Recent advances in small molecule fluorescent probes for simultaneous imaging of two bioactive molecules

Yongqing Zhou, Xin Wang, Wei Zhang, Bo Tang, Ping Li

Journal Article

Prevalence of antifolate drug resistance markers in in China

Journal Article